Llwytho...

DNA Damage-Induced Apoptosis and Mitogen-Activated Protein Kinase Pathway Contribute to the Toxicity of Dronedarone in Hepatic Cells

Dronedarone, an antiarrhythmic drug, has been marketed as an alternative to amiodarone. The use of dronedarone has been associated with severe liver injury; however, the mechanisms remain unclear. In this study, the possible mechanisms of dronedarone induced liver toxicity were characterized in HepG...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Environ Mol Mutagen
Prif Awduron: Chen, Si, Ren, Zhen, Yu, Dianke, Ning, Baitang, Guo, Lei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941192/
https://ncbi.nlm.nih.gov/pubmed/29399883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22173
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