Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants

Many bacteria and actinomycetales use L-cysteine biosynthesis to increase their tolerance to antibacterial treatment and establish a long-lasting infection. In turn, this might lead to the onset of antimicrobial resistance that currently represents one of the most menacing threats to public health w...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Magalhães, Joana, Franko, Nina, Raboni, Samanta, Annunziato, Giannamaria, Tammela, Päivi, Bruno, Agostino, Bettati, Stefano, Armao, Stefano, Spadini, Costanza, Cabassi, Clotilde Silvia, Mozzarelli, Andrea, Pieroni, Marco, Campanini, Barbara, Costantino, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931047/
https://ncbi.nlm.nih.gov/pubmed/33672408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14020174
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