Inhibition of Nonessential Bacterial Targets: Discovery of a Novel Serine O-Acetyltransferase Inhibitor

[Image: see text] In ϒ-proteobacteria and Actinomycetales, cysteine biosynthetic enzymes are indispensable during persistence and become dispensable during growth or acute infection. The biosynthetic machinery required to convert inorganic sulfur into cysteine is absent in mammals; therefore, it is...

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Xehetasun bibliografikoak
Argitaratua izan da:ACS Med Chem Lett
Egile Nagusiak: Magalhães, Joana, Franko, Nina, Raboni, Samanta, Annunziato, Giannamaria, Tammela, Päivi, Bruno, Agostino, Bettati, Stefano, Mozzarelli, Andrea, Pieroni, Marco, Campanini, Barbara, Costantino, Gabriele
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2020
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236226/
https://ncbi.nlm.nih.gov/pubmed/32435386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00627
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