Influenza hemagglutinin-specific IgA Fc-effector functionality is restricted to stalk epitopes

In this study, we utilized a panel of human immunoglobulin (Ig) IgA monoclonal antibodies isolated from the plasmablasts of eight donors after 2014/2015 influenza virus vaccination (Fluarix) to study the binding and functional specificities of this isotype. In this cohort, isolated IgA monoclonal an...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Freyn, Alec W., Han, Julianna, Guthmiller, Jenna J., Bailey, Mark J., Neu, Karlynn, Turner, Hannah L., Rosado, Victoria C., Chromikova, Veronika, Huang, Min, Strohmeier, Shirin, Liu, Sean T. H., Simon, Viviana, Krammer, Florian, Ward, Andrew B., Palese, Peter, Wilson, Patrick C., Nachbagauer, Raffael
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923359/
https://ncbi.nlm.nih.gov/pubmed/33593910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2018102118
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