A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment

Despite the development of effective therapies, a substantial proportion of asthmatics continue to have uncontrolled symptoms, airflow limitation, and exacerbations. Transient receptor potential cation channel member A1 (TRPA1) agonists are elevated in human asthmatic airways, and in rodents, TRPA1...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Exp Med
Autors principals: Balestrini, Alessia, Joseph, Victory, Dourado, Michelle, Reese, Rebecca M., Shields, Shannon D., Rougé, Lionel, Bravo, Daniel D., Chernov-Rogan, Tania, Austin, Cary D., Chen, Huifen, Wang, Lan, Villemure, Elisia, Shore, Daniel G.M., Verma, Vishal A., Hu, Baihua, Chen, Yong, Leong, Laurie, Bjornson, Chris, Hötzel, Kathy, Gogineni, Alvin, Lee, Wyne P., Suto, Eric, Wu, Xiumin, Liu, John, Zhang, Juan, Gandham, Vineela, Wang, Jianyong, Payandeh, Jian, Ciferri, Claudio, Estevez, Alberto, Arthur, Christopher P., Kortmann, Jens, Wong, Ryan L., Heredia, Jose E., Doerr, Jonas, Jung, Min, Vander Heiden, Jason A., Roose-Girma, Merone, Tam, Lucinda, Barck, Kai H., Carano, Richard A.D., Ding, Han Ting, Brillantes, Bobby, Tam, Christine, Yang, Xiaoying, Gao, Simon S., Ly, Justin Q., Liu, Liling, Chen, Liuxi, Liederer, Bianca M., Lin, Joseph H., Magnuson, Steven, Chen, Jun, Hackos, David H., Elstrott, Justin, Rohou, Alexis, Safina, Brian S., Volgraf, Matthew, Bauer, Rebecca N., Riol-Blanco, Lorena
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918756/
https://ncbi.nlm.nih.gov/pubmed/33620419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201637
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars