Behavioral characterization of a CRISPR-generated TRPA1 knockout rat in models of pain, itch, and asthma

The transient receptor potential (TRP) superfamily of ion channels has garnered significant attention by the pharmaceutical industry. In particular, TRP channels showing high levels of expression in sensory neurons such as TRPV1, TRPA1, and TRPM8, have been considered as targets for indications wher...

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Vydáno v:Sci Rep
Hlavní autoři: Reese, Rebecca M., Dourado, Michelle, Anderson, Keith, Warming, Søren, Stark, Kimberly L., Balestrini, Alessia, Suto, Eric, Lee, Wyne, Riol-Blanco, Lorena, Shields, Shannon D., Hackos, David H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976688/
https://ncbi.nlm.nih.gov/pubmed/31969645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57936-5
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