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The Ion Channel TRPA1 Is Required for Chronic Itch

Chronic itch is a debilitating condition that affects one in 10 people. Little is known about the molecules that mediate chronic itch in primary sensory neurons and skin. We demonstrate that the ion channel TRPA1 is required for chronic itch. Using a mouse model of chronic itch, we show that scratch...

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Detalhes bibliográficos
Main Authors: Wilson, Sarah R., Nelson, Aislyn M., Batia, Lyn, Morita, Takeshi, Estandian, Daniel, Owens, David M., Lumpkin, Ellen A., Bautista, Diana M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752436/
https://ncbi.nlm.nih.gov/pubmed/23719797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5318-12.2013
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