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S1PR3 Mediates Itch and Pain via Distinct TRP Channel-Dependent Pathways
Sphingosine 1-phosphate (S1P) is a bioactive signaling lipid associated with a variety of chronic pain and itch disorders. S1P signaling has been linked to cutaneous pain, but its role in itch has not yet been studied. Here, we find that S1P triggers itch and pain in male mice in a concentration-dep...
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| Published in: | J Neurosci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Society for Neuroscience
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6125817/ https://ncbi.nlm.nih.gov/pubmed/30082422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1266-18.2018 |
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