The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli

BACKGROUND & AIMS: The transient receptor potential (TRP) channel family includes transducers of mechanical and chemical stimuli for visceral sensory neurons. TRPA1 is implicated in inflammatory pain; it interacts with G-protein-coupled receptors, but little is known about its role in the gastro...

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Detalhes bibliográficos
Main Authors: Brierley, Stuart M., Hughes, Patrick A., Page, Amanda J., Kwan, Kelvin Y., Martin, Christopher M., O’Donnell, Tracey A., Cooper, Nicole J., Harrington, Andrea M., Adam, Birgit, Liebregts, Tobias, Holtmann, Gerald, Corey, David P., Rychkov, Grigori Y., Blackshaw, L. Ashley
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789877/
https://ncbi.nlm.nih.gov/pubmed/19632231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.07.048
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