TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity

ABSTRACT: The mechanosensory role of TRPA1 and its contribution to mechanical hypersensitivity in sensory neurons remains enigmatic. We elucidated this role by recording mechanically activated currents in conjunction with TRPA1 over- and under-expression and selective pharmacology. First, we establi...

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Detalhes bibliográficos
Main Authors: Brierley, Stuart M, Castro, Joel, Harrington, Andrea M, Hughes, Patrick A, Page, Amanda J, Rychkov, Grigori Y, Blackshaw, L Ashley
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Alimentary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167119/
https://ncbi.nlm.nih.gov/pubmed/21558163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.206789
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