TRPA1 Contributes to Cold Hypersensitivity

TRPA1 is a nonselective cation channel expressed by nociceptors. Although it is widely accepted that TRPA1 serves as a broad irritancy receptor for a variety of reactive chemicals, its role in cold sensation remains controversial. Here, we demonstrate that mild cooling markedly increases agonist-evo...

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Autori principali: del Camino, Donato, Murphy, Sarah, Heiry, Melissa, Barrett, Lee B., Earley, Taryn J., Cook, Colby A., Petrus, Matt J., Zhao, Michael, D'Amours, Marc, Deering, Nate, Brenner, Gary J., Costigan, Michael, Hayward, Neil J., Chong, Jayhong A., Fanger, Christopher M., Woolf, Clifford J., Patapoutian, Ardem, Moran, Magdalene M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021322/
https://ncbi.nlm.nih.gov/pubmed/21068322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2580-10.2010
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