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Various signals involved in nociception regulate TRPA1 levels at the plasma membrane

Transient receptor potential A1 (TRPA1) ion channel senses a variety of noxious stimuli, and is involved in nociception. Many TRPA1 agonists covalently modify the channel and can lead to desensitization. The fate of modified TRPA1 and the mechanism of preserving its response to subsequent stimuli ar...

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Detalhes bibliográficos
Main Authors: Schmidt, Manuela, Dubin, Adrienne E., Petrus, Matt J., Earley, Taryn J., Patapoutian, Ardem
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854037/
https://ncbi.nlm.nih.gov/pubmed/19945392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.09.030
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