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Identification of Transmembrane Domain 5 as a Critical Molecular Determinant of Menthol Sensitivity in Mammalian TRPA1 Channels

TRPA1 is a member of the transient receptor potential (TRP) family of ion channels and is expressed in a subset of nociceptive neurons. An increasing body of evidence suggests that TRPA1 functions as a chemical nocisensor for a variety of reactive chemicals, such as pungent natural compounds and env...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xiao, Bailong, Dubin, Adrienne E., Bursulaya, Badry, Viswanath, Veena, Jegla, Timothy J., Patapoutian, Ardem
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678945/
https://ncbi.nlm.nih.gov/pubmed/18815250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2772-08.2008
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