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Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain
TRPV1 is the founding and best-studied member of the family of temperature-activated transient receptor potential ion channels (thermoTRPs). Voltage, chemicals, and heat amongst other agonists allosterically gate TRPV1. Molecular determinants for TRPV1 activation by capsaicin, allicin, acid, ammonia...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876202/ https://ncbi.nlm.nih.gov/pubmed/20414199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2552 |
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