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Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain

TRPV1 is the founding and best-studied member of the family of temperature-activated transient receptor potential ion channels (thermoTRPs). Voltage, chemicals, and heat amongst other agonists allosterically gate TRPV1. Molecular determinants for TRPV1 activation by capsaicin, allicin, acid, ammonia...

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Hlavní autoři: Grandl, Jörg, Kim, Sung Eun, Uzzell, Valerie, Bursulaya, Badry, Petrus, Matt, Bandell, Michael, Patapoutian, Ardem
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876202/
https://ncbi.nlm.nih.gov/pubmed/20414199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2552
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