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Single Residues in the Outer Pore of TRPV1 and TRPV3 Have Temperature-Dependent Conformations

Thermosensation is mediated by ion channels that are highly temperature-sensitive. Several members of the family of transient receptor potential (TRP) ion channels are activated by cold or hot temperatures and have been shown to function as temperature sensors in vivo. The molecular mechanism of tem...

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Autori principali: Kim, Sung Eun, Patapoutian, Ardem, Grandl, Jörg
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608658/
https://ncbi.nlm.nih.gov/pubmed/23555720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059593
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