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Piezos are pore-forming subunits of mechanically activated channels

Mechanotransduction plays a crucial role in physiology. Biological processes including sensing touch and sound waves require yet unidentified cation channels that detect pressure. Mouse piezo1 (mpiezo1) and mpiezo2 induce mechanically activated cationic currents in cells; however, it is unknown if p...

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Hlavní autoři: Coste, Bertrand, Xiao, Bailong, Santos, Jose S., Syeda, Ruhma, Grandl, Jörg, Spencer, Kathryn S., Kim, Sung Eun, Schmidt, Manuela, Mathur, Jayanti, Dubin, Adrienne E., Montal, Mauricio, Patapoutian, Ardem
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297710/
https://ncbi.nlm.nih.gov/pubmed/22343900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10812
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