Piezo1 ion channel pore properties are dictated by C-terminal region

Piezo1 and Piezo2 encode mechanically activated cation channels that function as mechanotransducers involved in vascular system development and touch sensing, respectively. Structural features of Piezos remain unknown. Mouse Piezo1 is bioinformatically predicted to have 30–40 transmembrane (TM) doma...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Coste, Bertrand, Murthy, Swetha E., Mathur, Jayanti, Schmidt, Manuela, Mechioukhi, Yasmine, Delmas, Patrick, Patapoutian, Ardem
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445471/
https://ncbi.nlm.nih.gov/pubmed/26008989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8223
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