Piezo1 ion channel pore properties are dictated by C-terminal region

Piezo1 and Piezo2 encode mechanically activated cation channels that function as mechanotransducers involved in vascular system development and touch sensing, respectively. Structural features of Piezos remain unknown. Mouse Piezo1 is bioinformatically predicted to have 30–40 transmembrane (TM) doma...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Coste, Bertrand, Murthy, Swetha E., Mathur, Jayanti, Schmidt, Manuela, Mechioukhi, Yasmine, Delmas, Patrick, Patapoutian, Ardem
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445471/
https://ncbi.nlm.nih.gov/pubmed/26008989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8223
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