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Inflammatory Signals Enhance Piezo2-Mediated Mechanosensitive Currents
Heightened nociceptor function caused by inflammatory mediators such as bradykinin contributes to increased pain perception (hyperalgesia) to noxious mechanical and thermal stimuli. While sensitization of the heat transducer TRPV1 largely subserves thermal hyperalgesia, cellular mechanisms underlyin...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3462303/ https://ncbi.nlm.nih.gov/pubmed/22921401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.07.014 |
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