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Structure of the Mechanically Activated Ion Channel Piezo1

Piezo1 and Piezo2 are mechanically activated ion channels that mediate touch perception, proprioception, and vascular development. Piezos are distinct from other ion channels and their structure remains poorly defined, impeding detailed study of their gating and ion permeation properties. Here, we r...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Saotome, Kei, Murthy, Swetha E., Kefauver, Jennifer M., Whitwam, Tess, Patapoutian, Ardem, Ward, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010196/
https://ncbi.nlm.nih.gov/pubmed/29261642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25453
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