OSCA/TMEM63 are an evolutionarily conserved family of mechanically activated ion channels

Mechanically activated (MA) ion channels convert physical forces into electrical signals, and are essential for eukaryotic physiology. Despite their importance, few bona-fide MA channels have been described in plants and animals. Here, we show that various members of the OSCA and TMEM63 family of pr...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Murthy, Swetha E, Dubin, Adrienne E, Whitwam, Tess, Jojoa-Cruz, Sebastian, Cahalan, Stuart M, Mousavi, Seyed Ali Reza, Ward, Andrew B, Patapoutian, Ardem
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Evolutionary Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235560/
https://ncbi.nlm.nih.gov/pubmed/30382938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41844
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