OSCA/TMEM63 are an evolutionarily conserved family of mechanically activated ion channels

Mechanically activated (MA) ion channels convert physical forces into electrical signals, and are essential for eukaryotic physiology. Despite their importance, few bona-fide MA channels have been described in plants and animals. Here, we show that various members of the OSCA and TMEM63 family of pr...

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Pubblicato in:eLife
Autori principali: Murthy, Swetha E, Dubin, Adrienne E, Whitwam, Tess, Jojoa-Cruz, Sebastian, Cahalan, Stuart M, Mousavi, Seyed Ali Reza, Ward, Andrew B, Patapoutian, Ardem
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2018
Soggetti:
Evolutionary Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235560/
https://ncbi.nlm.nih.gov/pubmed/30382938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41844
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