Endogenous Piezo1 can confound mechanically-activated channel identification and characterization

A gold standard for characterizing mechanically-activated (MA) currents is via heterologous expression of candidate channels in naïve cells. Two recent studies described MA channels using this paradigm. TMEM150c was proposed to be a component of a MA channel partly based on a heterologous expression...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuron
Prif Awduron: Dubin, Adrienne E., Murthy, Swetha, Lewis, Amanda H., Brosse, Lucie, Cahalan, Stuart M., Grandl, Jörg, Coste, Bertrand, Patapoutian, Ardem
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448662/
https://ncbi.nlm.nih.gov/pubmed/28426961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.03.039
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg