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Piezos are pore-forming subunits of mechanically activated channels

Mechanotransduction plays a crucial role in physiology. Biological processes including sensing touch and sound waves require yet unidentified cation channels that detect pressure. Mouse piezo1 (mpiezo1) and mpiezo2 induce mechanically activated cationic currents in cells; however, it is unknown if p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Coste, Bertrand, Xiao, Bailong, Santos, Jose S., Syeda, Ruhma, Grandl, Jörg, Spencer, Kathryn S., Kim, Sung Eun, Schmidt, Manuela, Mathur, Jayanti, Dubin, Adrienne E., Montal, Mauricio, Patapoutian, Ardem
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297710/
https://ncbi.nlm.nih.gov/pubmed/22343900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10812
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