TRPV1 Is Activated by Both Acidic and Basic pH

Maintaining physiological pH is required for survival, and exposure to alkaline chemicals such as ammonia (smelling salts) elicits severe pain and inflammation through unknown mechanisms. TRPV1, the capsaicin receptor, is an integrator of noxious stimuli including heat and extracellular acidic pH. H...

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Detalhes bibliográficos
Main Authors: Dhaka, Ajay, Uzzell, Valerie, Dubin, Adrienne E., Mathur, Jayanti, Petrus, Matt, Bandell, Michael, Patapoutian, Ardem
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729567/
https://ncbi.nlm.nih.gov/pubmed/19129393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4901-08.2009
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