A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition

Mechanical hyperalgesia is a clinically-relevant form of pain sensitization that develops through largely unknown mechanisms. TRPA1, a Transient Receptor Potential ion channel, is a sensor of pungent chemicals that may play a role in acute noxious mechanosensation and cold thermosensation. We have d...

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Bibliografiska uppgifter
Huvudupphovsmän: Petrus, Matt, Peier, Andrea M, Bandell, Michael, Hwang, Sun Wook, Huynh, Truc, Olney, Nicholas, Jegla, Tim, Patapoutian, Ardem
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2007
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222610/
https://ncbi.nlm.nih.gov/pubmed/18086313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-3-40
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