PPARγ-p53-Mediated Vasculoregenerative Program to Reverse Pulmonary Hypertension

RATIONALE: In pulmonary arterial hypertension (PAH), endothelial dysfunction and obliterative vascular disease are associated with DNA damage and impaired signaling of bone morphogenetic protein type 2 receptor (BMPR2) via two downstream transcription factors, PPARγ and p53. OBJECTIVE: We investigat...

詳細記述

保存先:
書誌詳細
出版年:Circ Res
主要な著者: Hennigs, Jan K., Cao, Aiqin, Li, Caiyun G., Shi, Minyi, Mienert, Julia, Miyagawa, Kazuya, Körbelin, Jakob, Marciano, David P., Chen, Pin-I, Roughley, Matthew, Elliott, Matthew V., Harper, Rebecca L., Bill, Matthew, Chappell, James, Moonen, Jan-Renier, Diebold, Isabel, Wang, Lingli, Snyder, Michael P, Rabinovitch, Marlene
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7908816/
https://ncbi.nlm.nih.gov/pubmed/33322916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.119.316339
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