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Comprehensive in silico analysis and molecular dynamics of the superoxide dismutase 1 (SOD1) variants related to amyotrophic lateral sclerosis

Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disorder, with a significant social and economic burden. ALS remains incurable, and the only drugs approved for its treatments confers a survival benefit of a few months for the patients. Missense mutations in superoxide dismutase...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Pereira, Gabriel Rodrigues Coutinho, Vieira, Bárbara de Azevedo Abrahim, De Mesquita, Joelma Freire
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906464/
https://ncbi.nlm.nih.gov/pubmed/33630959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247841
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