Comprehensive in silico analysis and molecular dynamics of the superoxide dismutase 1 (SOD1) variants related to amyotrophic lateral sclerosis

Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disorder, with a significant social and economic burden. ALS remains incurable, and the only drugs approved for its treatments confers a survival benefit of a few months for the patients. Missense mutations in superoxide dismutase...

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Bibliographic Details
Published in:PLoS One
Main Authors: Pereira, Gabriel Rodrigues Coutinho, Vieira, Bárbara de Azevedo Abrahim, De Mesquita, Joelma Freire
Format: Artigo
Language:Inglês
Published: Public Library of Science 2021
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906464/
https://ncbi.nlm.nih.gov/pubmed/33630959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247841
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