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Structural and Functional Analysis of Human SOD1 in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with familial inheritance (fALS) in 5% to 10% of cases; 25% of those are caused by mutations in the superoxide dismutase 1 (SOD1) protein. More than 100 mutations in the SOD1 gene have been associated with fALS, altering the ge...

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Detalhes bibliográficos
Main Authors: Moreira, Lorenna Giannini Alves, Pereira, Livia Costa, Drummond, Priscila Ramalho, De Mesquita, Joelma Freire
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846731/
https://ncbi.nlm.nih.gov/pubmed/24312616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081979
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