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SOD1 Oligomers in Amyotrophic Lateral Sclerosis
Identifying nonnative, trimeric forms of SOD1 trimers as the toxic species, rather than large aggregates revolutionizes our understanding of ALS pathophysiology. Large protein aggregates, what was previously thought as the central cause of neurodegeneration, play protective role and are not responsi...
שמור ב:
| הוצא לאור ב: | Curr Opin Struct Biol |
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| Main Authors: | , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2021
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7965251/ https://ncbi.nlm.nih.gov/pubmed/33465527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2020.12.002 |
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