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SOD1 Oligomers in Amyotrophic Lateral Sclerosis

Identifying nonnative, trimeric forms of SOD1 trimers as the toxic species, rather than large aggregates revolutionizes our understanding of ALS pathophysiology. Large protein aggregates, what was previously thought as the central cause of neurodegeneration, play protective role and are not responsi...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Curr Opin Struct Biol
Päätekijät: Choi, Esther S, Dokholyan, Nikolay V
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7965251/
https://ncbi.nlm.nih.gov/pubmed/33465527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2020.12.002
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