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Is SOD1 loss of function involved in amyotrophic lateral sclerosis?
Mutations in the gene superoxide dismutase 1 (SOD1) are causative for familial forms of the neurodegenerative disease amyotrophic lateral sclerosis. When the first SOD1 mutations were identified they were postulated to give rise to amyotrophic lateral sclerosis through a loss of function mechanism,...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3722346/ https://ncbi.nlm.nih.gov/pubmed/23687121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awt097 |
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