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In silico analysis of PFN1 related to amyotrophic lateral sclerosis

Profilin 1 (PFN1) protein plays key roles in neuronal growth and differentiation, membrane trafficking, and regulation of the actin cytoskeleton. Four natural variants of PFN1 were described as related to ALS, the most common adult-onset motor neuron disorder. However, the pathological mechanism of...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Pereira, Gabriel Rodrigues Coutinho, Tellini, Giovanni Henrique Almeida Silva, De Mesquita, Joelma Freire
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583998/
https://ncbi.nlm.nih.gov/pubmed/31216283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215723
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