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In silico analysis of PFN1 related to amyotrophic lateral sclerosis
Profilin 1 (PFN1) protein plays key roles in neuronal growth and differentiation, membrane trafficking, and regulation of the actin cytoskeleton. Four natural variants of PFN1 were described as related to ALS, the most common adult-onset motor neuron disorder. However, the pathological mechanism of...
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| Published in: | PLoS One |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6583998/ https://ncbi.nlm.nih.gov/pubmed/31216283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215723 |
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