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In silico analysis of the tryptophan hydroxylase 2 (TPH2) protein variants related to psychiatric disorders

The tryptophan hydroxylase 2 (TPH2) enzyme catalyzes the first step of serotonin biosynthesis. Serotonin is known for its role in several homeostatic systems related to sleep, mood, and food intake. As the reaction catalyzed by TPH2 is the rate-limiting step of serotonin biosynthesis, mutations in T...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pereira, Gabriel Rodrigues Coutinho, Tavares, Gustavo Duarte Bocayuva, de Freitas, Marta Costa, De Mesquita, Joelma Freire
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051086/
https://ncbi.nlm.nih.gov/pubmed/32119710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229730
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