In silico analysis of the V66M variant of human BDNF in psychiatric disorders: An approach to precision medicine

Brain-derived neurotrophic factor (BDNF) plays an important role in neurogenesis and synapse formation. The V66M is the most prevalent BDNF mutation in humans and impairs the function and distribution of BDNF. This mutation is related to several psychiatric disorders. The pro-region of BDNF, particu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: De Oliveira, Clara Carolina Silva, Pereira, Gabriel Rodrigues Coutinho, De Alcantara, Jamile Yvis Santos, Antunes, Deborah, Caffarena, Ernesto Raul, De Mesquita, Joelma Freire
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472887/
https://ncbi.nlm.nih.gov/pubmed/30998730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215508
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