PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness

Pluripotent stem cells (PSCs) have a unique energetic and biosynthetic metabolism compared with typically differentiated cells. However, the metabolism profiling of PSCs and its underlying mechanism are still unclear. Here, we report PSCs metabolism profiling and identify the purine synthesis enzyme...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Yang, Yi, Song, Lili, Huang, Xia, Feng, Yanan, Zhang, Yingwen, Liu, Yanfeng, Li, Shanshan, Zhan, Zhiyan, Zheng, Liang, Feng, Haizhong, Li, Yanxin
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2021
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906169/
https://ncbi.nlm.nih.gov/pubmed/33493137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202372
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