PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness

Pluripotent stem cells (PSCs) have a unique energetic and biosynthetic metabolism compared with typically differentiated cells. However, the metabolism profiling of PSCs and its underlying mechanism are still unclear. Here, we report PSCs metabolism profiling and identify the purine synthesis enzyme...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Aging (Albany NY)
Hlavní autoři: Yang, Yi, Song, Lili, Huang, Xia, Feng, Yanan, Zhang, Yingwen, Liu, Yanfeng, Li, Shanshan, Zhan, Zhiyan, Zheng, Liang, Feng, Haizhong, Li, Yanxin
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals 2021
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906169/
https://ncbi.nlm.nih.gov/pubmed/33493137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202372
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