PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness

Pluripotent stem cells (PSCs) have a unique energetic and biosynthetic metabolism compared with typically differentiated cells. However, the metabolism profiling of PSCs and its underlying mechanism are still unclear. Here, we report PSCs metabolism profiling and identify the purine synthesis enzyme...

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Sparad:
Bibliografiska uppgifter
I publikationen:Aging (Albany NY)
Huvudupphovsmän: Yang, Yi, Song, Lili, Huang, Xia, Feng, Yanan, Zhang, Yingwen, Liu, Yanfeng, Li, Shanshan, Zhan, Zhiyan, Zheng, Liang, Feng, Haizhong, Li, Yanxin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals 2021
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906169/
https://ncbi.nlm.nih.gov/pubmed/33493137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202372
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