PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness

Pluripotent stem cells (PSCs) have a unique energetic and biosynthetic metabolism compared with typically differentiated cells. However, the metabolism profiling of PSCs and its underlying mechanism are still unclear. Here, we report PSCs metabolism profiling and identify the purine synthesis enzyme...

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Bibliografski detalji
Izdano u:Aging (Albany NY)
Glavni autori: Yang, Yi, Song, Lili, Huang, Xia, Feng, Yanan, Zhang, Yingwen, Liu, Yanfeng, Li, Shanshan, Zhan, Zhiyan, Zheng, Liang, Feng, Haizhong, Li, Yanxin
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals 2021
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906169/
https://ncbi.nlm.nih.gov/pubmed/33493137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202372
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