Super-enhancer mediated regulation of adult β-globin gene expression: the role of eRNA and Integrator

Super-enhancers (SEs) mediate high transcription levels of target genes. Previous studies have shown that SEs recruit transcription complexes and generate enhancer RNAs (eRNAs). We characterized transcription at the human and murine β-globin locus control region (LCR) SE. We found that the human LCR...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Gurumurthy, Aishwarya, Yu, David T, Stees, Jared R, Chamales, Pamela, Gavrilova, Ekaterina, Wassel, Paul, Li, Lu, Stribling, Daniel, Chen, Jinyang, Brackett, Marissa, Ishov, Alexander M, Xie, Mingyi, Bungert, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897481/
https://ncbi.nlm.nih.gov/pubmed/33476375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab002
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados