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Engineering Globin Gene Expression

Hemoglobinopathies, including sickle cell disease and thalassemia, are among the most common inherited genetic diseases worldwide. Due to the relative ease of isolating and genetically modifying hematopoietic stem and progenitor cells, recent gene editing and gene therapy strategies have progressed...

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Dettagli Bibliografici
Pubblicato in:Mol Ther Methods Clin Dev
Autori principali: Davis, Rachael, Gurumurthy, Aishwarya, Hossain, Mir A., Gunn, Eliot M., Bungert, Jörg
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310746/
https://ncbi.nlm.nih.gov/pubmed/30603654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.12.004
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