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Phase separation and transcription regulation: Are super-enhancers and locus control regions primary sites of transcription complex assembly?
We propose that the multiple enhancer elements associated with locus control regions and super-enhancers recruit RNA polymerase II and efficiently assemble elongation competent transcription complexes that are transferred to target genes by transcription termination and transient looping mechanisms....
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| Publicado no: | Bioessays |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6484441/ https://ncbi.nlm.nih.gov/pubmed/30500078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201800164 |
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