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Coordination of transcription, processing, and export of highly expressed RNAs by distinct biomolecular condensates

Genes under control of super-enhancers are expressed at extremely high levels and are frequently associated with nuclear speckles. Recent data suggest that the high concentration of unphosphorylated RNA polymerase II (Pol II) and Mediator recruited to super-enhancers create phase-separated condensat...

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Detalhes bibliográficos
Publicado no:Emerg Top Life Sci
Main Authors: Ishov, Alexander M., Gurumurthy, Aishwarya, Bungert, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733674/
https://ncbi.nlm.nih.gov/pubmed/32338276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/ETLS20190160
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