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Coordination of transcription, processing, and export of highly expressed RNAs by distinct biomolecular condensates

Genes under control of super-enhancers are expressed at extremely high levels and are frequently associated with nuclear speckles. Recent data suggest that the high concentration of unphosphorylated RNA polymerase II (Pol II) and Mediator recruited to super-enhancers create phase-separated condensat...

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Foilsithe in:Emerg Top Life Sci
Main Authors: Ishov, Alexander M., Gurumurthy, Aishwarya, Bungert, Jörg
Formáid: Artigo
Teanga:Inglês
Foilsithe: Portland Press Ltd. 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733674/
https://ncbi.nlm.nih.gov/pubmed/32338276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/ETLS20190160
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