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Distinctive Patterns of Transcription and RNA Processing for Human lincRNAs

Numerous long intervening noncoding RNAs (lincRNAs) are generated from the mammalian genome by RNA polymerase II (Pol II) transcription. Although multiple functions have been ascribed to lincRNAs, their synthesis and turnover remain poorly characterized. Here, we define systematic differences in tra...

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Publicat a:Mol Cell
Autors principals: Schlackow, Margarita, Nojima, Takayuki, Gomes, Tomas, Dhir, Ashish, Carmo-Fonseca, Maria, Proudfoot, Nick J.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222723/
https://ncbi.nlm.nih.gov/pubmed/28017589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.11.029
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