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Distinctive Patterns of Transcription and RNA Processing for Human lincRNAs

Numerous long intervening noncoding RNAs (lincRNAs) are generated from the mammalian genome by RNA polymerase II (Pol II) transcription. Although multiple functions have been ascribed to lincRNAs, their synthesis and turnover remain poorly characterized. Here, we define systematic differences in tra...

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Bibliographic Details
Published in:Mol Cell
Main Authors: Schlackow, Margarita, Nojima, Takayuki, Gomes, Tomas, Dhir, Ashish, Carmo-Fonseca, Maria, Proudfoot, Nick J.
Format: Artigo
Language:Inglês
Published: Cell Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222723/
https://ncbi.nlm.nih.gov/pubmed/28017589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.11.029
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