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Coordination of transcription, processing, and export of highly expressed RNAs by distinct biomolecular condensates
Genes under control of super-enhancers are expressed at extremely high levels and are frequently associated with nuclear speckles. Recent data suggest that the high concentration of unphosphorylated RNA polymerase II (Pol II) and Mediator recruited to super-enhancers create phase-separated condensat...
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| Veröffentlicht in: | Emerg Top Life Sci |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Portland Press Ltd.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7733674/ https://ncbi.nlm.nih.gov/pubmed/32338276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/ETLS20190160 |
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