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Phase separation and transcription regulation: Are super-enhancers and locus control regions primary sites of transcription complex assembly?
We propose that the multiple enhancer elements associated with locus control regions and super-enhancers recruit RNA polymerase II and efficiently assemble elongation competent transcription complexes that are transferred to target genes by transcription termination and transient looping mechanisms....
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| Pubblicato in: | Bioessays |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6484441/ https://ncbi.nlm.nih.gov/pubmed/30500078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201800164 |
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