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Dissecting the function of the adult β-globin downstream promoter region using an artificial zinc finger DNA-binding domain

Developmental stage-specific expression of the β-type globin genes is regulated by many cis- and trans-acting components. The adult β-globin gene contains an E-box located 60 bp downstream of the transcription start site that has been shown to bind transcription factor upstream stimulatory factor (U...

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Bibliografske podrobnosti
Main Authors: Barrow, Joeva J., Li, Ying, Hossain, Mir, Huang, Suming, Bungert, Jörg
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985677/
https://ncbi.nlm.nih.gov/pubmed/24497190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku107
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