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Dissecting the function of the adult β-globin downstream promoter region using an artificial zinc finger DNA-binding domain
Developmental stage-specific expression of the β-type globin genes is regulated by many cis- and trans-acting components. The adult β-globin gene contains an E-box located 60 bp downstream of the transcription start site that has been shown to bind transcription factor upstream stimulatory factor (U...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985677/ https://ncbi.nlm.nih.gov/pubmed/24497190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku107 |
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