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Neutralizing the function of a β-globin–associated cis-regulatory DNA element using an artificial zinc finger DNA-binding domain
Gene expression is primarily regulated by cis-regulatory DNA elements and trans-interacting proteins. Transcription factors bind in a DNA sequence–specific manner and recruit activities that modulate the association and activity of transcription complexes at specific genes. Often, transcription fact...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497758/ https://ncbi.nlm.nih.gov/pubmed/23074246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207677109 |
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