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The Influence of cis-Regulatory Elements on DNA Methylation Fidelity

It is now established that, as compared to normal cells, the cancer cell genome has an overall inverse distribution of DNA methylation (“methylome”), i.e., predominant hypomethylation and localized hypermethylation, within “CpG islands” (CGIs). Moreover, although cancer cells have reduced methylatio...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Teng, Mingxiang, Balch, Curt, Liu, Yunlong, Li, Meng, Huang, Tim H. M., Wang, Yadong, Nephew, Kenneth P., Li, Lang
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295790/
https://ncbi.nlm.nih.gov/pubmed/22412954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032928
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